Science
BedSharkPal
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1y ago
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One night of total sleep deprivation shown to have antidepressant effect for some people
https://medicalxpress.com/news/2023-07-night-total-deprivation-shown-antidepressant.htmlMajor depression has previously been associated with abnormalities in REM sleep. Excess REM sleep would diminish noradrenaline, resulting in decreased binding to the ɑ-2 receptor in the medial frontal lobes comprised of the ACC and the medial prefrontal cortex. The absence of REM sleep with TSD may give some participants a break to improve top-down control of the amygdala, resulting in an antidepressant effect.
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